Beta-hydroxy-beta-methylbutyric acid (HMB) is widely found in citrus fruits, certain vegetables such as broccoli, legumes such as alfalfa, and certain fish and seafood. Beta-hydroxy-beta-methylbutyric acid (HMB), as a metabolite of leucine, has been shown to increase muscle synthesis, reduce muscle breakdown, and has anti-inflammatory effects. The conversion of HMB into stable β-hydroxy-β-methylbutyrate calcium salt (HMB-CA) has been widely used in sports nutrition and other foods, which can play a special nutritional role