HMB-Ca promotes muscle growth

The effect of HMB Ca (β - hydroxy - β - methylbutyrate calcium) on muscle growth is mainly reflected in the following mechanisms and effects:

1、 Core mechanism of action

Inhibit protein breakdown

HMB Ca significantly reduces the rate of muscle protein breakdown by blocking the ubiquitin proteasome pathway.

Promote protein synthesis

Stimulate protein synthesis within muscle cells and enhance the function of the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis.

Protecting the structure of muscle cells

Maintain sarcomere integrity, reduce skeletal muscle damage and cell apoptosis caused by exercise, and accelerate the recovery process.

2、 Specific effects on muscle growth

Increase muscle mass and strength

When combined with resistance training, daily supplementation of 38 mg/kg body weight of HMB Ca (approximately 3 grams/day) can sustainably improve lean body mass and muscle strength.

For the elderly population: significantly delaying the progression of sarcopenia, improving muscle function and quality of life.

Reduce muscle damage after exercise

Reduce serum creatine kinase (CK) levels, alleviate delayed onset muscle soreness (DOMS), and accelerate recovery after exercise.

Assist in fat metabolism

When combined with regular exercise, it can synergistically reduce fat mass and optimize body composition ratio.

3、 Key application points

Dose and timing

Recommended dosage: 3 grams per day (FDA approved safety limit);

Best time to take: 1-2 hours before training (HMB Ca takes longer to absorb).

Applicable population

Sports enthusiasts (enhancing muscle endurance and explosive power);

Elderly people (fighting muscle loss);

Postoperative or long-term bed rest (reducing muscle atrophy).

Form differences

The bioavailability of HMB Ca is lower than that of the free acid form (HMB-FA), which absorbs faster but has not been fully studied